Technology Platforms

Technology Platforms

Anji Biotech has been deeply engaged in innovative peptide drug R&D. Relying on its four self-developed core technology platforms, the company has built a fully integrated peptide drug R&D system covering novel target discovery and endogenous micropeptide identification, precise rational design of targeted peptide molecules, drug conjugation optimization, and systematic druggability evaluation — spanning the entire process from early discovery, molecular optimization and druggability assessment to preclinical validation.

Through its high-throughput novel target and micropeptide discovery platform, the company has established an efficient, high-throughput system for endogenous micropeptide discovery. Leveraging bioinformatics analysis, high-throughput screening systems and differentiated target validation technologies, it precisely identifies and validates novel functional targets and micropeptides, breaking through the industry pain points of single-source targets and molecular homogeneity in traditional peptide drugs, and continuously expanding the boundaries and applications of peptide drug R&D while providing core molecular reserves and target support for source-level innovative drug development.

Building on its structure-targeted peptide computer-aided rational design platform, Anji Biotech integrates years of peptide drug R&D experience to achieve precise and intelligent innovative design of peptide molecules.

Its peptide-conjugated drug platform focuses on precision delivery technologies for peptide drugs, flexibly adapting to R&D needs across different mechanisms of action to develop diversified conjugated peptide molecular structures.

The supporting druggability evaluation platform provides a comprehensive peptide drug druggability assessment system, enabling rapid screening of candidate molecules early in drug development and substantially shortening peptide drug R&D cycles while reducing overall development costs.

The four platforms work in efficient synergy and deep interconnection, forming a closed-loop core capability for innovative peptide drug R&D that combines source-level innovation vitality with industrial translation advantages. Driven by these technology platforms, the company continues to address unmet clinical needs, focus on high-value innovative peptide drugs, and is committed to building an innovative drug pipeline with distinctive differentiation and sustainable iteration.

High-Throughput Novel Target & Micropeptide Discovery Technology Platform

Since peptides opened the modern path of biomedicine, frontier science has been rewriting the code of life. The landmark discovery that non-coding RNA encodes micropeptides has unlocked a treasure trove of novel targets. Seizing the opportunity of the times, Anji Biotech has mastered the core technology for high-throughput discovery of endogenous micropeptides. Rooted in original fundamental theories and translational platforms, the company is exploring the immense value of micropeptides in disease diagnosis and treatment, and pursuing a new generation of innovative drugs.

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Structure-Targeted Peptide Computer-Aided Rational Design Technology Platform

Anji Biotech has been deeply engaged in peptide design and development, accumulating systematic experience covering target structure elucidation, peptide structure-activity relationships, key amino acid identification, sequence optimization, cyclization and peptidomimetic modification, half-life regulation, and peptide conjugate development. Unlike platforms that rely solely on algorithms or large-scale random library construction, STP-CADD continuously distills the team's years of peptide design principles, global failure cases, experimental data and druggability experience into computational models and standardized design workflows, enabling the platform not only to identify sequences that "theoretically can bind", but also to judge "which sequences are more likely to be synthesized, validated and further developed".

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Peptide-Conjugated Drug Technology Platform

Based on structure-targeted peptides derived from Anji's two peptide source technologies, specific linkers are selected to conjugate with toxins, nuclides, nucleic acids and other drugs to enable development of PDC, PRC, POC and APC drugs. Fully leveraging the rapid enrichment advantage of peptides, the platform achieves rapid accumulation of different types of molecules in the target region, with relatively stable metabolism, fully ensuring sustained effective concentrations over the long term.

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Druggability Evaluation Technology Platform

The company has a comprehensive and rapid peptide druggability evaluation platform, including a peptide drug design and discovery platform, a peptide synthesis platform, systematic preclinical pharmaceutical research, pharmacodynamics research, pharmacokinetics research platforms, an SPF-grade animal facility and a GMP-standard cell facility, providing comprehensive and rapid peptide druggability evaluation.

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